U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Granulomatous inflammatory arthritis, dermatitis and uveitis, familial(ACUG)

MedGen UID:
348835
Concept ID:
C1861303
Disease or Syndrome
Synonyms: Arthrocutaneouveal granulomatosis; Blau syndrome; Early-Onset Sarcoidosis; Familial Granulomatosis, Blau Type; Familial Juvenile Systemic Granulomatosis; Granulomatosis, familial juvenile systemic; Granulomatosis, familial, Blau type; Granulomatous inflammatory arthritis, dermatitis, and uveitis, familial; Jabs syndrome; Pediatric Granulomatous Arthritis; Synovitis granulomatous with uveitis and cranial neuropathies; Synovitis, Granulomatous, With Uveitis And Cranial Neuropathies
SNOMED CT: Arthrocutaneouveal granulamotosis (699861000); Familial juvenile systemic granulomatosis (699861000); Familial granulomatosis, Blau type (699861000); Pediatric granulomatous arthritis (699861000); Familial granulomatous inflammatory arthritis, dermatitis and uveitis (699861000); Granulomatous inflammatory arthritis, dermatitis and uveitis, familial (699861000)
 
OMIM®: 186580

Recent clinical studies

Etiology

Rodrigues FG, Petrushkin H, Webster AR, Bickerstaff M, Moraitis E, Rowczenio D, Aróstegui JI, Westcott M
Ophthalmic Genet 2021 Dec;42(6):753-764. Epub 2021 Jul 12 doi: 10.1080/13816810.2021.1946701. PMID: 34251956
Rosé CD, Aróstegui JI, Martin TM, Espada G, Scalzi L, Yagüe J, Rosenbaum JT, Modesto C, Cristina Arnal M, Merino R, García-Consuegra J, Carballo Silva MA, Wouters CH
Arthritis Rheum 2009 Jun;60(6):1797-803. doi: 10.1002/art.24533. PMID: 19479837Free PMC Article
Schaffer JV, Chandra P, Keegan BR, Heller P, Shin HT
Arch Dermatol 2007 Mar;143(3):386-91. doi: 10.1001/archderm.143.3.386. PMID: 17372104
Becker ML, Rose CD
Curr Rheumatol Rep 2005 Dec;7(6):427-33. doi: 10.1007/s11926-005-0046-3. PMID: 16303101

Diagnosis

Baisya R, Manthri R, Tyagi M, Uppin SG, Rajasekhar L
Clin Immunol 2023 Oct;255:109743. Epub 2023 Aug 20 doi: 10.1016/j.clim.2023.109743. PMID: 37604356
Kumrah R, Pilania RK, Menia NK, Rawat A, Sharma J, Gupta A, Vignesh P, Jindal AK, Rikhi R, Agarwal A, Gupta V, Singh S, Suri D
Front Immunol 2022;13:932919. Epub 2022 Sep 15 doi: 10.3389/fimmu.2022.932919. PMID: 36189202Free PMC Article
Punzi L, Gava A, Galozzi P, Sfriso P
Best Pract Res Clin Rheumatol 2011 Oct;25(5):703-14. doi: 10.1016/j.berh.2011.10.017. PMID: 22142748
Becker ML, Rose CD
Curr Rheumatol Rep 2005 Dec;7(6):427-33. doi: 10.1007/s11926-005-0046-3. PMID: 16303101
Blau EB
J Pediatr 1985 Nov;107(5):689-93. doi: 10.1016/s0022-3476(85)80394-2. PMID: 4056967

Therapy

Kumrah R, Pilania RK, Menia NK, Rawat A, Sharma J, Gupta A, Vignesh P, Jindal AK, Rikhi R, Agarwal A, Gupta V, Singh S, Suri D
Front Immunol 2022;13:932919. Epub 2022 Sep 15 doi: 10.3389/fimmu.2022.932919. PMID: 36189202Free PMC Article
Okazaki F, Wakiguchi H, Korenaga Y, Nakamura T, Yasudo H, Uchi S, Yanai R, Asano N, Hoshii Y, Tanabe T, Izawa K, Honda Y, Nishikomori R, Uchida K, Eishi Y, Ohga S, Hasegawa S
Pediatr Rheumatol Online J 2021 Feb 18;19(1):18. doi: 10.1186/s12969-021-00505-5. PMID: 33602264Free PMC Article
Ebrahimiadib N, Samra KA, Domina AM, Stiles ER, Ewer R, Bocian CP, Foster CS
Ocul Immunol Inflamm 2018;26(1):57-64. Epub 2016 Jul 15 doi: 10.1080/09273948.2016.1185529. PMID: 27419275
Çakan M, Keskindemirci G, Aydoğmuş Ç, Akı H, Hatipoğlu N, Kıyak A, Aydoğan G, Aktay-Ayaz N
Turk J Pediatr 2016;58(5):545-549. doi: 10.24953/turkjped.2016.05.015. PMID: 28621099
Martin TM, Zhang Z, Kurz P, Rosé CD, Chen H, Lu H, Planck SR, Davey MP, Rosenbaum JT
Arthritis Rheum 2009 Feb;60(2):611-8. doi: 10.1002/art.24222. PMID: 19180500Free PMC Article

Prognosis

Rodrigues FG, Petrushkin H, Webster AR, Bickerstaff M, Moraitis E, Rowczenio D, Aróstegui JI, Westcott M
Ophthalmic Genet 2021 Dec;42(6):753-764. Epub 2021 Jul 12 doi: 10.1080/13816810.2021.1946701. PMID: 34251956
Becker ML, Rose CD
Curr Rheumatol Rep 2005 Dec;7(6):427-33. doi: 10.1007/s11926-005-0046-3. PMID: 16303101

Clinical prediction guides

Kumrah R, Pilania RK, Menia NK, Rawat A, Sharma J, Gupta A, Vignesh P, Jindal AK, Rikhi R, Agarwal A, Gupta V, Singh S, Suri D
Front Immunol 2022;13:932919. Epub 2022 Sep 15 doi: 10.3389/fimmu.2022.932919. PMID: 36189202Free PMC Article
Rodrigues FG, Petrushkin H, Webster AR, Bickerstaff M, Moraitis E, Rowczenio D, Aróstegui JI, Westcott M
Ophthalmic Genet 2021 Dec;42(6):753-764. Epub 2021 Jul 12 doi: 10.1080/13816810.2021.1946701. PMID: 34251956
Sfriso P, Caso F, Tognon S, Galozzi P, Gava A, Punzi L
Autoimmun Rev 2012 Nov;12(1):44-51. Epub 2012 Aug 2 doi: 10.1016/j.autrev.2012.07.028. PMID: 22884558
Rosé CD, Wouters CH, Meiorin S, Doyle TM, Davey MP, Rosenbaum JT, Martin TM
Arthritis Rheum 2006 Oct;54(10):3337-44. doi: 10.1002/art.22122. PMID: 17009307
Crowson AN, Magro CM
Hum Pathol 1997 Apr;28(4):478-84. doi: 10.1016/s0046-8177(97)90038-1. PMID: 9104949

Supplemental Content

Table of contents

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...